Sequencing technologies and genome sequencing
نویسندگان
چکیده
منابع مشابه
Applying Rapid Genome Sequencing Technologies
of diseases under a variety of scenarios suggest that infectious diseases will continue to negatively impact the health of human populations well into the future (1). Although economic, social, and technological developments will surely influence these projections, the impact of the constantly changing interaction between hosts and infectious agents is rarely considered. Throughout evolutionary...
متن کاملComparing whole genome sequencing and exome sequencing
Introduction Next-generation DNA sequencing empowers scientists to identify genetic variations associated with human disease at higher resolution and greater sensitivity than previously possible. Two approaches are commonly employed -exome sequencing and whole genome sequencing. Exome sequencing targets protein-coding regions comprising approximately 1% of the human genome, while whole genome s...
متن کاملGenome Sequencing
The concept of genome sequencing is quite simple. Break your genome up into many different small fragments, clone those fragments into a cloning vector, isolate many clones, and sequence each clone. All of the techniques used for sequencing are well established. These are the same techniques that scientists used for the past twenty years to characterize many different individual genes. Using th...
متن کاملLecture 16: Sequencing Technologies
Introduction This lecture covered current and state-of-the-art methods in genome sequencing, and covered mostly biological topics and not algorithmic ones. Sequencing is the process of determining the complete order of nucleotides present in a DNA strand. This is a fundamental process for much of computational biology, as alignment, motif discovery, the Extended Haplotype Homozygocity test, and...
متن کاملHigh-throughput sequencing technologies.
The human genome sequence has profoundly altered our understanding of biology, human diversity, and disease. The path from the first draft sequence to our nascent era of personal genomes and genomic medicine has been made possible only because of the extraordinary advancements in DNA sequencing technologies over the past 10 years. Here, we discuss commonly used high-throughput sequencing platfo...
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ژورنال
عنوان ژورنال: Journal of Applied Genetics
سال: 2011
ISSN: 1234-1983,2190-3883
DOI: 10.1007/s13353-011-0057-x